A new rapid diagnostic test developed at the University of California, Berkeley, is drawing attention for its innovative use of a common phenomenon observed in drying coffee spills. The project began when Kamyar Behrouzi, then an engineering PhD candidate at UC Berkeley, noticed how particles in spilled coffee migrate to the outer edge as it dries—a pattern known as the “coffee-ring effect.” This observation led to the creation of a medical test that leverages this effect to concentrate disease markers and make them easier to detect.
“Watch this short video –– part of our ongoing series called Born at UC Berkeley –– to learn more about the innovation from our student host, Angela Zhang.”
The new test involves applying a swab sample onto a membrane. As the liquid dries, particles gather into a ring shape. Researchers then add a solution containing plasmonic nanoparticles. If disease biomarkers are present in the sample, these nanoparticles bind to them and form visible patterns that change how light interacts with the membrane.
The process delivers results in as little as 12 minutes and has demonstrated accuracy surpassing that of existing rapid COVID-19 tests. According to researchers, this approach could be adapted for detecting conditions such as sepsis, COVID-19, influenza, and some cancers.
“The innovation is another example of how fundamental science can lead to practical, potentially life-saving technologies born at UC Berkeley. Read more about the discovery here, and follow UC Berkeley on Instagram, YouTube and other social platforms to see more videos like this.”
UC Berkeley is recognized for addressing global challenges through research and interdisciplinary collaboration according to its official website. The university was founded in 1868 and operates from its campus in Berkeley, California as described on its official site. It offers over 300 degree programs across 15 schools and colleges and employs more than 1,500 faculty members according to university sources.
